L-tryptophan and the eosinophilia-myalgia syndrome

[L-tryptophan and the eosinophilia-myalgia syndrome].

L-tryptophan and eosinophilia-myalgia syndrome.

L-Tryptophan and Eosinophilia-Myalgia Syndrome Participant's Guide Learning Objectives After completing this case study, the participant should be able to: Discuss issues related to rapid establishment of national surveillance for a newly recognized and little understood disorder. Discuss development of case definitions. Describe the elements of design and the advantages and disadvantages of ca...

L-tryptophan induced eosinophilia-myalgia syndrome.

We describe the spectrum of clinical and histologic abnormalities of 11 women with L-tryptophan induced eosinophilia-myalgia syndrome. The illness is characterized by musculoskeletal symptoms including myalgias, arthralgias and paresthesias. The physical findings consist of muscle tenderness, neuropathies, rash, peripheral and periorbital edema. Electroneurography performed in 10 patients demon...

L-tryptophan implicated in human eosinophilia-myalgia syndrome causes fasciitis and perimyositis in the Lewis rat.

Tryptophan-associated eosinophilia-myalgia syndrome (L-TRP-EMS) is a newly described syndrome which occurred in epidemic fashion in the United States in the summer and fall of 1989. Epidemiologic data has linked the syndrome to intake of L-tryptophan (L-TRP) from one specific manufacturer, but the precise etiologic compound(s) must be established by replication of the syndrome in an appropriate...

L-tryptophan induced cough and pleural effusions associated with the eosinophilia-myalgia syndrome.

Communications to the Editor are basically in agreement with his statements, we feel a few comments are in order. The extremely high rate of specific benign diagnoses reported by Khouri et al’ from needle biopsies of lung nodules is not the experience of most practitioners, and is probably due to their unique expertise, as well as the fact that in most instances they used an 18 or 20 ga needle ...